Skip to main content
. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: NMR Biomed. 2014 Dec 15;28(2):217–230. doi: 10.1002/nbm.3237

Figure 10.

Figure 10

(a) Simulation of Z-spectra of multiple PARACEST agents in a muscle-like water/MT system at 9.4T for different B1 (1,3,6μT) after 2 s of irradiation. Simulation (dots) and analytical solution (lines) match also in the case of large MT contribution at B1=6μT. The PARACEST pools were assumed to have the same R1=0.7 Hz, and R2=30.30 Hz, and fractions f=0.2%, with exchange rates of 1000Hz at 45ppm, 2000 Hz at 50 and 5000Hz at 55ppm. (b) Simulation of Z-spectra of endogenous CEST effects apparent in white brain matter with a shifted semi-solid MT (at −2.6ppm, fc=13.9%) at 7T for different B1 after 10 s of irradiation. The used NOE concentration was 2.39 %. Amide and amide concentration was set to 0.2%. kamide was 30 Hz, kamine = 1500 Hz and kNOE=20 Hz.