Table 1.

Detailed Clinical, Pathological, and Molecular Characteristics of 29 Paired Medulloblastomas Sampled at Diagnosis and Relapse Showing Altered and Acquired Features at Relapse

Demographic frequencies and altered and acquired events are shown as a proportion and percentage of the data available for each variable. D, diagnosis; R, relapse. Consensus molecular subgroup: red, SHH/MB_SHH; blue, WNT/MB_WNT; yellow, G3/MB_Group3; green, G4/MB_Group4. Pathology variant: CLA, classic; LCA, large-cell/anaplastic; DN, desmoplastic/nodular; NOS, medulloblastoma not otherwise specified. Disease location: local, M0/M1; distant, M2+. Biopsy site: gray square, primary tumor biopsied; white square, metastatic site biopsied; U, biopsy site unknown; crossed square, biopsy sample not available. Current status: ADF, alive disease-free; DOD, died of disease; DOTC, died of treatment complications. Chromosome 17 status: red, loss; green, gain. Other categories: gray square, feature present; white square, feature absent; crossed square, data not available. See also Table S1 and S2.