Table 1.
Marker | Test | Results |
---|---|---|
PSA | IHC | Focally positive |
PAP | IHC | Diffusely positive |
PSMA | IHC | Diffusely positive |
AMACR | IHC | Diffusely positive |
AR | IHC | Diffusely positive (nuclear) |
ERG | IHC | Diffusely positive (nuclear) |
Nkx3.1 | IHC | Diffusely positive (nuclear) |
Chromogranin | IHC | Diffusely positive |
Synaptophysin | IHC | Diffusely positive |
CD56 | IHC | Diffusely positive |
Ki67 | IHC | Up to 35% |
CK7 | IHC | Negative |
CK20 | IHC | Negative |
TTF-1 | IHC | Negative |
p63 | IHC | Negative |
GATA-3 | IHC | Negative |
Pten | FISH | Negative for hetero- and homozygotic deletion |