Figure 3.
Survival rate in irradiated mice under different transplantation regimens. Within 12 hours of receiving a 3.5 Gy dose of 60Co total irradiation, 12 mice in each experimental group were transplanted with the indicated cell types via the tail vein. The survival rate of animals were recorded daily after transplantation. SDF-1: SDF-1/MSCs+ CD34+ cells; HOXB4: HOXB4/MSCs+ CD34+ cells; S-H: SDF1-HOXB4/MSCs+ CD34+ cells; MSC-HSC: MSCs+ CD34+ cells; HSC: CD34+ cells alone; IR: irradiated mice injected with 0.3 ml physiological saline. *P < 0.05 vs all other groups; #P < 0.05 vs IR, HSC, MSC + HSC, and HOXB4 groups, respectively.