Figure 3.

Effects of valproate treatment on functional stroke outcome and infarct volume. Comparisons of functional stroke outcomes (A-C) and infarct volume (D) were made at the three-month follow-up for patients in the valproate (n = 14) and non-valproate (n = 12) groups. Significant improvements were seen for on all scale scores for the valproate group (A) National Institutes of Health stroke scale (NIHSS), (B) modified Rankin scale (mRS), and (C) Barthel index (BI). No such improvement was seen in the non-valproate group for the NIHSS and mRS, and only modest improvement was seen in the BI scale (A-C). Meanwhile, no significant change of infarct volume (D) was found as comparison of the stroke lesion in FLAIR imaging between the two-week and three-month of follow up at both individual group. Vertical bars represent standard errors of the means. Statistical significance was determined by paired t-test.