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. Author manuscript; available in PMC: 2016 Feb 15.
Published in final edited form as: Biol Psychiatry. 2014 Aug 27;77(4):404–415. doi: 10.1016/j.biopsych.2014.07.033

Fig. 3. Anxiety-related behaviours.

Fig. 3

(A) Open Field. Distance travelled (left) and time spent in center (right) did not differ across genotypes. (B) Elevated plus-maze. Dlx-DOR showed increased time in open arms (left) and a trend to more entries in those arms (right) compared to Ctrl mice. General activity was similar (total visits) between the two groups (data not shown), reflecting no change in spontaneous locomotor activity. (C) Novelty suppressed feeding. Latency to feed was decreased (left), and accordingly number of approaches was decreased also (right) in Dlx-DOR mice compared with Ctrl mice. n=16 per genotype, and filled stars represent significant differences compare to Ctrl mice. One star, P<0.05; two stars, P<0.01; three stars, P<0.001 (Student t-test).