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. Author manuscript; available in PMC: 2016 Jan 15.
Published in final edited form as: Cell. 2014 Dec 24;160(0):74–87. doi: 10.1016/j.cell.2014.12.011

Figure 7. IL-4Rα signaling in mature adipocytes is dispensable for growth of beige fat.

Figure 7

(A) Histological analysis of scWAT of 5-week-old Il4raf/f and Il4raf/f/AdipoqCre mice housed at 22°C. Representative sections were stained with hematoxylin and eosin, and images are shown at 100× magnification (top panels) and 400× magnification (bottom panels). (B) Immunoblot analysis of UCP1 protein expression in scWAT and BAT of 5-week-old Il4raf/f and Il4raf/f/AdipoqCre mice. (C–F) Assessment of energy expenditure in 5 week-old Il4raf/f and Il4raf/f/AdipoqCre mice was performed using CLAMS; (C) oxygen consumption (VO2), (D) RER, (E) food intake, and (F) total activity. Data are represented as mean ± SEM.