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. Author manuscript; available in PMC: 2016 Jan 16.
Published in final edited form as: Circ Res. 2014 Oct 27;116(2):e13–e24. doi: 10.1161/CIRCRESAHA.116.304794

Figure 3. Aortic root lesions of GM-CSF-deficient Ldlr−/− mice have lower levels of IL-23.

Figure 3

A–B, RNA was isolated by LCM of lesional cells in 12 wk WD-fed Ldlr−/− and Csf2−/−Ldlr−/− mice, and mRNA of the indicated genes was quantified by RT-qPCR. All data are normalized to Actb mRNA. n=5 mice per group; *, p<0.05; n.s., no significant difference. C, Atherosclerotic lesional extracts obtained from 12 wk WD-fed Ldlr−/− and Csf2−/−Ldlr−/− mice were assayed for IL-23 by ELISA. n=10 mice per group; *, p<0.05; n.s., no significant difference.