Table 1.
miRNAs differentially regulated in MCF7:2A vs. MCF7 cells.
| miRNA | Fold Change | pvalue | Location | ER binding site |
|---|---|---|---|---|
| hsa-miR-148a-3p | 10.6 | 3.9E-20 | Intergenic | No |
| hsa-miR-20a-5p/hsa-miR-20b-5p | 6.5 | 4.4E-13 | MIR17HG | No |
| hsa-miR-218-5p | 6.1 | 2.2E-14 | SLIT3 | Yes |
| hsa-miR-19a-3p | 5.3 | 2.3E-09 | MIR17HG | No |
| hsa-miR-19b-3p | 5.3 | 2.6E-14 | MIR17HG | No |
| hsa-miR-106a-5p/hsa-miR-17-5p | 4.9 | 1.0E-10 | Intergenic | No |
| hsa-miR-32-5p | 4.6 | 1.2E-11 | TMEM245 | Yes |
| hsa-miR-590-5p | 4.3 | 2.4E-10 | EIF4H | Yes |
| hsa-miR-92a-3p | 4.3 | 5.4E-04 | MIR17HG | Yes |
| hsa-miR-30a-5p | 4.0 | 1.6E-09 | Intergenic | No |
| hsa-miR-135b-5p | 4.0 | 5.4E-08 | Intergenic | Yes |
| hsa-miR-29b-3p | 4.0 | 2.9E-10 | Intergenic | Yes |
| hsa-miR-210 | 3.5 | 3.5E-07 | MIR210HG | Yes |
| hsa-miR-18a-5p | 3.2 | 1.8E-06 | MIR17HG | No |
| hsa-miR-30b-5p | 2.5 | 4.7E-03 | Intergenic | Yes |
| hsa-miR-660-5p | 2.5 | 2.1E-04 | CLCN5 | No |
| hsa-miR-33a-5p | 2.5 | 2.8E-04 | SREBF2 | No |
| hsa-miR-590-3p | 2.3 | 7.7E-04 | EIF4H | Yes |
| hsa-miR-1180 | 2.3 | 1.5E-04 | B9D1 | Yes |
| hsa-miR-98 | 2.3 | 8.2E-05 | HUWE1 | Yes |
| hsa-miR-296-5p | 2.3 | 2.7E-03 | Intergenic | No |
| hsa-miR-1245a | 2.3 | 4.5E-02 | COL3A1 | No |
| hsa-miR-186-5p | 2.3 | 8.6E-04 | ZRANB2 | No |
| hsa-miR-497-5p | 2.1 | 3.1E-03 | MIR497HG | No |
| hsa-miR-16-5p | 2.1 | 1.4E-03 | DLEU2 | Yes |
| hsa-miR-135a-5p | 2.1 | 1.5E-02 | GLYCTK | Yes |
| hsa-miR-203 | 2.1 | 8.8E-04 | Intergenic | Yes |
| hsa-let-7i-5p | 2.0 | 6.7E-04 | Intergenic | Yes |
| hsa-miR-30d-5p | 2.0 | 1.7E-03 | Intergenic | Yes |
| hsa-miR-30e-5p | 2.0 | 1.5E-03 | NFYC | Yes |
| hsa-miR-652-3p | 2.0 | 4.2E-03 | TMEM164 | Yes |
| hsa-let-7d-5p | 2.0 | 1.8E-03 | MIRLET7DHG | No |
| hsa-miR-324-5p | 2.0 | 2.9E-03 | ACADVL | Yes |
| hsa-miR-30c-5p | 2.0 | 3.0E-03 | NFYC | Yes |
| hsa-miR-505-3p | 2.0 | 1.3E-02 | Intergenic | No |
| hsa-miR-23b-3p | 1.9 | 3.9E-02 | C9ORF3 | Yes |
| hsa-miR-423-3p | 1.9 | 5.3E-03 | NSRP1 | No |
| hsa-miR-503 | 1.9 | 7.2E-03 | MGC16121 | Yes |
| hsa-miR-362-3p | 1.9 | 1.7E-02 | CLCN5 | No |
| hsa-miR-107 | 1.9 | 1.3E-02 | PANK1 | No |
| hsa-miR-195-5p | 1.7 | 1.7E-02 | MIR497HG | No |
| hsa-miR-1183 | 1.7 | 1.3E-02 | SP4 | No |
| hsa-miR-361-5p | 1.7 | 8.4E-03 | CHM | No |
| hsa-miR-574-3p | 1.7 | 1.9E-02 | FAM114A1 | Yes |
| hsa-miR-148b-3p | 1.7 | 1.1E-02 | COPZ1 | Yes |
| hsa-miR-1226-3p | 1.7 | 5.0E-02 | DHX30 | Yes |
| hsa-miR-301a-3p | 1.7 | 4.0E-02 | SKA2 | No |
| hsa-miR-362-3p | 1.6 | 4.5E-02 | CLCN5 | No |
| hsa-miR-769-5p | 1.6 | 3.9E-02 | Intergenic | No |
| hsa-miR-378a-3p/hsa-miR-378i | 1.6 | 3.9E-02 | PPARGC1B | Yes |
| hsa-miR-185-5p | 1.6 | 4.3E-02 | TANGO2 | Yes |
| hsa-miR-106b-5p | 1.6 | 4.7E-02 | MCM7 | Yes |
| hsa-miR-331-3p | 1.6 | 3.7E-02 | Intergenic | No |
| hsa-miR-29c-3p | 1.6 | 4.7E-02 | Intergenic | Yes |
| hsa-miR-22-3p | −1.6 | 2.4E-02 | MIR22HG | Yes |
| hsa-miR-222-3p | −1.6 | 3.8E-02 | Intergenic | No |
| hsa-miR-95 | −1.6 | 2.4E-02 | ABLIM2 | Yes |
| hsa-miR-145-5p | −1.7 | 4.2E-02 | MIR143HG | Yes |
| hsa-miR-663a | −1.7 | 3.8E-02 | LOC284801 | No |
| hsa-miR-215 | −1.9 | 3.7E-02 | IARS2 | No |
| hsa-miR-4516 | −2.0 | 1.2E-02 | PKD1 | Yes |
| hsa-miR-504 | −2.0 | 2.9E-03 | FGF13 | No |
| hsa-miR-887 | −2.0 | 4.9E-02 | FBXL7 | No |
| hsa-miR-3187-3p | −2.1 | 2.8E-02 | LPPR3 | Yes |
| hsa-miR-1185-5p | −2.1 | 3.4E-02 | Intergenic | No |
| hsa-miR-342-5p | −2.1 | 3.8E-02 | EVL | Yes |
| hsa-let-7c | −2.1 | 5.2E-04 | LINC00478 | Yes |
| hsa-miR-548m | −2.1 | 1.2E-02 | Intergenic | No |
| hsa-miR-3175 | −2.3 | 4.5E-03 | CHD2 | Yes |
| hsa-miR-200a-3p | −2.3 | 1.1E-03 | Intergenic | Yes |
| hsa-miR-100-5p | −2.3 | 3.6E-04 | MIG100HG | No |
| hsa-miR-149-5p | −2.6 | 1.9E-02 | GPC1 | Yes |
| hsa-miR-429 | −2.6 | 2.0E-04 | Intergenic | Yes |
| hsa-miR-221-3p | −3.0 | 6.5E-03 | Intergenic | No |
| hsa-miR-125b-5p | −4.0 | 3.0E-09 | LINC00478 | Yes |
| hsa-miR-1246 | −4.3 | 4.4E-06 | Intergenic | No |
| hsa-miR-489 | −5.7 | 1.1E-03 | CALCR | Yes |
| hsa-miR-99a-5p | −19.7 | 5.1E-25 | LINC00478 | Yes |