Table 5. Serious Adverse Events.

Patient	Pre-specified Infusion Associated Events	Other adverse events	Description
2	None	Death on day 9	Patient never recovered from ARDS/sepsis, developed worsening multi-organ failure and shock on study day 6, expired on study day 9.
3	None	Infarcts of kidneys, spleen, brain	Multiple, likely embolic infarcts of spleen, kidneys, and brain discovered incidentally on study day 0 and study day 1. Believed to have occurred prior to MSC infusion based on MRI results. Extensive work-up for embolic source was negative except for small abnormality of the mitral valve. Culture negative endocarditis was cited as a possible cause of emboli. Patient recovered and was discharged to an acute rehabilitation facility.
5	None	Respiratory arrest on day 24, death on day 31	Patient recovered from ARDS and was discharged from ICU. On study day 24 suffered respiratory arrest believed related to aspiration and was transferred back to ICU. Developed worsening multi-organ failure and expired on study day 31. No resuscitation was attempted in keeping with family wishes.