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Lowest level of quantification and the intra-assay percentage of coefficient of variation for the analytes measured by high performance liquid chromatography with tandem mass spectrometry.
| Analyte | LLOQ | % CV |
|---|---|---|
| TRP | 10 µM | 5.70 |
| KYN | 0.75 µM | 5.83 |
| KynA | 12.5 nM | 5.36 |
| 3HK | 10 nM | 4.50 |
| QA | 50 nM | 3.70 |
Note: The LLOQ and % CV data are derived from a group of subjects with MDD in addition to the BD subjects and healthy controls included in this study.
