Figure 6. tBHQ treatment inhibits NFκB DNA binding in PBMCs.
PBMCs were left untreated (Bkg), or pretreated with vehicle (Veh, 0.01% ethanol) or tBHQ (1µM), then activated 30 min later with anti-CD3/anti-CD28. 3h after activation, cells were collected and nuclear protein was isolated. p65 NFκB DNA binding activity was quantified spectrophotometrically by measuring absorbance at 450 nm.