Table 2.
Effects of various extracts of M. repandus on the latency time in tail immersion test.
Group |
Doses (mg/kg) | Latency time(s) |
||||
---|---|---|---|---|---|---|
0 h | 1 h | 2 h | 3 h | 4 h | ||
Control | 1% Tween 80 in water (10 mL/kg) | 4.462 ± 0.196 | 4.278 ± 0.370 | 4.404 ± 0.243 | 3.984 ± 0.334 | 3.936 ± 0.314 |
Pentazocine | 10 | 4.18 ± 0.256 | 8.4 ± 0.51* | 8.294 ± 0.250* | 8.028 ± 0.96* | 6.834 ± 0.282* |
MLM | 500 | 4.720 ± 0.343 | 5.540 ± 0.431 | 4.408 ± 0.556 | 5.138 ± 0.186 | 5.704 ± 0.639 |
1000 | 4.314 ± 0.136 | 5.990 ± 1.297 | 4.164 ± 0.468 | 5.058 ± 0.403 | 4.742 ± 0.511 | |
2000 | 4.778 ± 0.133 | 7.720 ± 1.136 | 6.250 ± 1.625* | 7.540 ± 1.282* | 6.080 ± 0.460* |
Values are presented in mean ± SEM (n = 5). * P < 0.05 was considered statistically significant when compared against control. Overall time effect is considered extremely significant with F (4, 80) = 5.910 and P < 0.05. Repeated measure ANOVA with Dunnet's multiple comparison was performed to analyze this data set.