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Helminthic regulation of cytokine production during GVHD.
| Uninfected | H. polygyrus | p value | |
|---|---|---|---|
| Donor T cell IFNγ (ng/ml) | 153.4±8.4 (N=3) | 54.7±33.9 (N=3) | p<0.05 |
| Donor T cell TNFα (ng/ml) | 8.0±0.3 (N=3) | 5.1±0.6 (N=3) | p<0.05 |
| Donor T cell IL4 (ng/ml) | 0.5±0.1 (N=3) | 2.8±0.4 (N=3) | p<0.05 |
| Serum IFNγ (ng/ml) | 2.0±0.12 (N=5) | 0.37±0.07 (N=5) | p<0.001 |
| Serum TNFα (ng/ml) | 1.9±0.3 (N=5) | 0.7±0.1 (N=5) | p<0.01 |
