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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Brain Res Bull. 2014 Dec 12;0:54–67. doi: 10.1016/j.brainresbull.2014.12.003

Figure 1.

Figure 1

Treatment effects on cholinesterase activity in whole brain on PN4, 2 hours after the final injection of chlorpyrifos (CPF) or vehicle (mean ± SE, n=6). Inhibition by chlorpyrifos was significantly enhanced by prenatal nicotine (Nic) treatment. One-factor ANOVA for the four treatment groups is shown at the top of the panel; asterisks denote the groups that differ significantly from the control value and the dagger indicates that the Nic+CPF group is different from CPF alone. Two-factor ANOVA showed a significant nicotine × chlorpyrifos interaction (p < 0.04), indicating the 25% decrease comparing Nic+CPF to nicotine alone is significantly greater than the 14% decrease evoked by CPF alone (CPF vs. Control). Values were combined for males and females because of the absence of a treatment × sex interaction.