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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Drug Alcohol Depend. 2014 Dec 18;0:1–19. doi: 10.1016/j.drugalcdep.2014.12.005

Figure 7.

Figure 7

Effects of DAT releasers on extracellular dopamine (DA) and horizontal locomotor activity (HLA) in male rats. Rats undergoing microdialysis in the n. accumbens received sequential intravenous doses of the fully efficacious releaser PAL 1046, the partial releaser PAL-1045 or saline vehicle. Arrows indicate time of injections (1 or 3 mg/kg i.v.). Dialysate DA concentrations were assayed by HPLC-ECD. Data are mean ± SEM for n=6-7 rats/group.