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. Author manuscript; available in PMC: 2016 Jan 15.
Published in final edited form as: J Neuroimmunol. 2014 Nov 26;0:289–298. doi: 10.1016/j.jneuroim.2014.11.020

Figure 1.

Figure 1

Splenectomy attenuates sex differences in infarct volume following experimental stroke in mice. Male and female mice were subject to sham splenectomy or splenectomy two weeks prior to transient MCAO (60 min). Brains were harvested 96 h after MCAO and brain slices were stained with 2,3,5-triphenyltetrazolium chloride (TTC) (A). Infarct volumes were measured as percentage of contralateral structure (B). Values represent mean numbers (±SEM) of 11 spleen-intact male and female mice; n=12 for splenectomized males and females. * indicates p<0.05 analyzed using a Two-Way ANOVA.