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. Author manuscript; available in PMC: 2016 Jan 15.
Published in final edited form as: J Neuroimmunol. 2014 Nov 26;0:289–298. doi: 10.1016/j.jneuroim.2014.11.020

Figure 6.

Figure 6

Splenectomy attenuates sex differences in activated microglia/monocytes in the ischemic brain following experimental stroke. Brains were harvested 96 hours after MCAO from spleen-intact and splenectomized mice, processed and immunophenotyped by flow cytometry. Infiltrating and activated monocytes/microglia was determined by gating on CD11b+ cells and examining CD45 high cells. Representative dot plots (A) and averages (B) of CD11b+CD45hi cell frequencies in the ischemic hemisphere are included. Values represent mean numbers (±SEM) of 8–9 mice from each group. * indicates p<0.05, ** indicates p <0.01.