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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: J Immunol. 2014 Dec 24;194(3):868–872. doi: 10.4049/jimmunol.1401193

Figure 1.

Figure 1

CLP-induced lymphocyte lymphopenia is C5a receptor-dependent. A) Blood leukocyte numbers 3 days after CLP in Wt mice or Wt, C5aR1−/−, and C5aR2−/− mice (n=5–10 mice per group). B) Splenic leukocyte numbers 3 days after CLP in Wt mice or Wt, C5aR1−/−, and C5aR2−/− mice (n=5 mice per group). C) Representative TUNEL labeling of spleen sections from Wt or C5aR1−/− mice 20 hrs after CLP (or sham Wt). The scale bar is for all images. D) Aggregate data from TUNEL labeling expressed as the number of TUNEL+ cells per microscopic field (n=5 mice per group).