Skip to main content
. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Mol Cancer Res. 2014 Aug 26;13(1):174–185. doi: 10.1158/1541-7786.MCR-14-0263

Figure 4.

Figure 4

Effect of host LPA receptor on the homing of B16F10 lung metastasis. (A) LPA1 KO mice had a reduced number of lung nodules. n = 11 WT mice, and n = 8 LPA1 KO mice. (B) H&E staining of lungs from WT (left panel) and LPA1 KO mice (right panel). (C) No differences in the number of lung nodules were observed between WT and LPA2 KO mice. n = 12 WT mice, and n = 9 LPA2 KO mice. (D) H&E staining of lungs from WT (left panel) and LPA2 KO mice (right panel). (E) LPA5 KO mice had a reduced number of lung nodules. n = 10 WT mice, and n = 12 LPA5 KO mice. (F) H&E staining of lungs from WT (left panel) and LPA5 KO mice (right panel). P values are relative to control WT mice. Scale bar = 500 microns.