Fig. 5.
Recovery AW after repetitive and incremental application of MCh. AWs were measured at 3 min after washout of various concentrations of MCh (see Fig. 2D-F). Then the measured AW was normalized to the initial AW in each slice (AW/AWini, A and B) or to the AW measured just before the application of MCh (C, AW/AWbasal). Comparison of control vs. Ova-asthma (A), and of control vs. IL-13TG (B). In C, summary of AW/AWbasal (%) for 1 and 10 µM of MCh in Ova-asthma and IL-13TG are shown as bar graphs. Albeit the apparent difference between control and Ova-asthma at 1 µM of MCh (A), statistical comparison shows p>0.05. Numbers of tested slices are directly indicated in figure.