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Foxd1−/− kidneys display abnormal subcapsular lymphatics. Immunostaining for the specific marker for lymphatic vascular endothelium (LYVE, brown) show in newborn kidneys of control mice (left) few lymphatic capillaries within the renal capsule and lymphatic vessels adjacent to a large vein (V) and artery (A), whereas in the Foxd1−/− kidneys, there are multiple large lymphatic vessels adjacent to aberrant capsular arteries and veins.
