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. 2014 Dec 11;4(1):155–169. doi: 10.1016/j.stemcr.2014.11.002

Table 2.

Enrichment for Tumor-Initiating Cells in SORE6+ Fractions from Three Human Breast Cancer Cell Lines

Cell Line Breast Cancer Subtype CSC Frequency SORE6− CSC Frequency SORE6+ Enrichment Factor p Value
MCF7-EP ER+ 1/9,097 >1/430 >21.1 1.2 × 10−09
MCF10Ca1h ER+ 1/14,308 1/722 19.8 6.9 × 10−08
MDA-MB-231 TNBC 1/549 1/58 9.5 4.5 × 10−08

Tumor cells at different dilutions were implanted orthotopically into nude mice, and tumor incidence was assessed after 1–3 months, depending on the model. CSC frequencies were calculated using ELDA software. p value is for chi-square test. ER, estrogen receptor; TNBC, triple-negative breast cancer.