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. 2014 Dec 11;4(1):47–60. doi: 10.1016/j.stemcr.2014.11.001

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© 2015 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).

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Transcriptome Comparison of iMOP and Otosphere Cells

(A) Heatmap of detectable transcripts from ESC, iMOP, and otosphere (OS) RNA-seq samples, plotted with relative read counts depicted by color.

(B) Differentially expressed genes from pairwise comparison between averaged iMOP samples and otospheres. Genes that displayed statistically significant differences (p < 0.05) were identified. Individual C-MYC and SOX2 target genes are noted on the heatmap on the right.

(C) Functions of differentially expressed genes (p < 0.05) from iMOP and otosphere samples. The table shows pertinent biological processes based on Gene Ontology analysis and the associated p value.

(D) Differential expression of significantly altered genes (p < 0.05) from Gene Ontology analysis from pairwise comparison of iMOP and OS samples.