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. 2014 Oct 31;3:47–55. doi: 10.1016/j.redox.2014.10.005

Fig. 7.

Fig. 7

Targeted catalase expression blunts Zn2+-induced HO-1 mRNA levels in BEAS cells. BEAS-2B cells overexpressing catalase (A) or expressing ectopic mitochondrial catalase (B) were exposed to the indicated Zn2+ concentrations and 1 µM PYRI for 5 min followed by 2 h in media alone. HO-1 mRNA levels were normalized to levels of GAPDH mRNA and expressed as fold increases over basal mRNA expression in control cells. Values are presented as mean±SE (n=3), * indicates p<0.05 as determined by ANCOVA compared to control.