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. 2014 Mar 13;2:599–609. doi: 10.1016/j.redox.2014.03.003

Fig. 1.

Fig. 1

Synergistic effects of non-toxic concentrations of efavirenz (EFV) and isoniazid (INH) on cell injury and intracellular ATP concentrations during exposure of cultured mouse hepatocytes to combined EFV/INH. Time course of (A) LDH release and (B) intracellular ATP content after treatment with solvent (DMSO, 0.1%), INH alone (1000 μM), EFV alone (30 μM), or combined EFV/INH. Data are mean ± SD of three independent hepatocyte preparations using quadruplicate wells. *P < 0.05 versus solvent control.