Table 1. Gene ontology annotation of differentially expressed genes in Panc02 tumors induced by enriched environment.
| No. | Term | Count | P | PFDR |
|---|---|---|---|---|
| Top 5 GO cellular component terms | ||||
| 1 | Mitochondrion | 69 | 3.50E-40 | 4.24E-37 |
| 2 | Mitochondrial part | 46 | 4.44E-34 | 5.40E-31 |
| 3 | Mitochondrial envelope | 32 | 5.80E-22 | 7.06E-19 |
| 4 | Mitochondrial inner membrane | 29 | 6.68E-22 | 8.13E-19 |
| 5 | Mitochondrial membrane | 31 | 1.36E-21 | 1.65E-18 |
| Top 5 GO biological process terms | ||||
| 1 | Generation of precursor metabolites and energy | 39 | 1.83E-39 | 2.76E-36 |
| 2 | Oxidation reduction | 41 | 3.66E-26 | 5.50E-23 |
| 3 | Cellular respiration | 17 | 2.47E-21 | 3.72E-18 |
| 4 | Electron transport chain | 20 | 5.76E-21 | 8.66E-18 |
| 5 | Acetyl-CoA metabolic process | 14 | 1.99E-20 | 3.00E-17 |
| Top 5 GO molecular function terms | ||||
| 1 | Coenzyme binding | 19 | 1.39E-15 | 1.91E-12 |
| 2 | Cofactor binding | 21 | 3.44E-15 | 4.55E-12 |
| 3 | NAD or NADH binding | 9 | 2.92E-09 | 3.87E-06 |
| 4 | Iron-sulfur cluster binding | 9 | 8.49E-09 | 1.12E-05 |
| 5 | Metal cluster binding | 9 | 8.49E-09 | 1.12E-05 |
GO: gene ontology; PFDR: false discovery rate corrected P value.