Skip to main content
. 2015 Jan 19;5:7830. doi: 10.1038/srep07830

Figure 5. Cellular pharmacology analysis of mifepristone.

Figure 5

A, in vitro activity of mifepristone against MDA-MB-231 cell line. B, dose-dependent inhibition by mifepristone on cell migration. A Corning transwell system was used to assay cell migration as described in methods. The amount of MDA-MB-231 cells migrated through polycarbonate membranes was counted by microscopic observation (10×). Each experiment was carried out at least three times. *, P < 0.05, **, P < 0.01. C, inhibition by mifepristone of MDA-MB-231 cells adhesion to HUVECs. Representative microscopic observation of the inhibition by mifepristone at 0, 50, and 100 μM. DMSO (0.1%) was used as vehicle control (average of 10 independent microscope fields for each of 3 independent experiments).