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. 2015 Jan 19;5:7878. doi: 10.1038/srep07878

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Groups of one-day-old BALB/c mice were inoculated i.p. with 100 LD₅₀ of EV-A71 (A) or 20 LD₅₀ of CVA16 (B), followed by administration of PBS, heat-treated anti-EV-A71, or anti-ChiEV-A71 sera, respectively, at 1 h post inoculation. The mortality were monitored and recorded daily for 21 days. *P < 0.05 for anti-ChiEV-A71 sera or anti-EV-A71 sera group vs. PBS group.