Table 5.
Samples | Dose (mg/kg) | Edema (mL × 10 −2 ) | Edema inhibition (%)* | |||||
---|---|---|---|---|---|---|---|---|
1 h | 3 h | 5 h | 1 h | 3 h | 5 h | |||
Control | - | 26 ± 2.75 | 57.5 ± 1.51 | 59 ± 3.27 | - | - | - | |
ASL (reference) | 300 | 17.66 ± 1.63 | 24.83 ± 1.72 | 29.33 ± 1.21 | 32.07 | 56.81 | 50.28 | |
Diclofenac (reference) | 10 | 15.66 ± 5.12 | 25.83 ± 2.40 | 28.66 ± 3.61 | 39.76 | 55.07 | 51.42 | |
Fucoidans | C. sedoides | 25 | 13.66 ± 3.20*** | 29.66 ± 5.20*** | 40.16 ± 4.70*** | 47.46a | 48.41a | 31.93a |
50 | 10.66 ± 4.08*** | 28.16 ± 3.38*** | 41.66 ± 1.21*** | 59.00b | 51.02a | 29.38a | ||
C. compressa | 25 | 12.66 ± 2.73*** | 26.83 ± 1.04*** | 29.83 ± 2.40*** | 51.30a | 53.33a | 49.44a | |
50 | 11.83 ± 4.09*** | 24.83 ± 2.48*** | 28.00 ± 2.36*** | 54.50a | 56.81a | 52.54a | ||
C. crinita | 25 | 12.66 ± 3.43*** | 26.50 ± 3.39*** | 19.83 ± 1.94*** | 51.28a | 54.17a | 66.38a | |
50 | 13.20 ± 2.68*** | 24.16 ± 2.56*** | 28.50 ± 2.50*** | 49.23a | 58.21a | 51.69b |
Data are expressed as mean ± s.e.m. (n = 6).
*Mean values with different superscript letters in the same row are significantly different at p ≤ 0.05.
***p < 0.001.