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. 2014 Dec 17;15(12):555. doi: 10.1186/s13059-014-0555-3

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© Anvar et al.; licensee BioMed Central. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Resolving the level of relatedness between microbiomes. (A) Three-dimensional scatter plot of the k-mer distance measures for a series of metagenomes with different copy number of three closely related species. (B) Scatter plot of the relative distance between Firmicutes and Proteobacteria phyla. Each data point represents a metagenome with a differing number of species from each phylum. Data points are colored according to the number of species from each phylum. (C) PCA plot of pairwise k-mer distance measures for gut microbiomes. Data points are colored based on the origin of the sample (male in blue and female in red) and time. (D) PCA plot of pairwise k-mer distance measures for right-palm microbiomes. (E) PCA plot of pairwise UniFrac distance measures for gut microbiomes. (F) PCA plot of pairwise UniFrac distance measures for right-palm microbiomes. PCA, principal component analysis.