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. 2014 Dec 28;11:27. doi: 10.1186/2045-8118-11-27

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© He et al.; licensee BioMed Central. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Histograms showing that SF EAE (ZT 0–12 SF) induced an increase over resting EAE mice in (A) the total number of CD4 ⁺ T cells and (B) the percent of CD4 ⁺ T cells among all leukocytes infiltrating the spinal cord on Day 16 of EAE (n = 8 /group). *: p < 0.05; **: p < 0.01; ***: p < 0.005.