Fig. 7.

Haplotype-block 12 and the evolved haplotypes from generation 67. Haplotype-block 12 from the base population is labeled with b5; 25 evolved haplotypes are labeled with e (four evolved haplotypes were excluded as <20% of their bases in that region were called). The left panel represents the haplotype block structure. Each horizontal line corresponds to one haplotype and each column to a singleton-SNP position within the base haplotypes. SNPs specific to haplotype-block 12 are indicated in blue, yellow indicates the remaining singletons in the base population. The major allele in the base population is shown in red. Missing data are shown in gray. The right panel shows a cladogram (average linkage clustering) based on singleton-SNP sharing. The blue rectangle marks the evolved haplotypes that cluster with b5. The core of the haplotype-block is shared among the three evolved haplotypes indicating no recombination in this region. As toward the end of the blocks singleton markers for b5 are scarce, it might be that the block has been called slightly too long.