Figure 2.

Ultraviolet (UV)-induced phosphorylation of c-Jun N-terminal kinase (JNK), extracellular signal-regulated kinase (ERK) and c-Jun. Human melanocytes were exposed to UVA (60 J cm⁻²) or UVB (500 mJ cm⁻²) and the resultant levels of phosphorylation were analysed by Western blotting at 2, 4, 6 and 24 h postirradiation. One representative Western blot out of four and the corresponding optical density of UVA-induced (a) phosphorylated JNK (p-JNK) and JNK, (c) phosphorylated ERK (p-ERK) and ERK, and (e) phosphorylated c-Jun (p-c-Jun) and c-Jun. UVB-induced (b) p-JNK and JNK, (d) p-ERK and ERK, and (f) p-c-Jun and c-Jun. The results are presented as the mean ± SD (four different donors). *P ≤ 0·05 vs. control.