Table 1.

Melanocytes were exposed to ultraviolet (UV)A and UVB irradiation and, after 4 h, the apoptotic fraction of cells was isolated and the mRNA expression compared with that of controls. The list presents selected genes of the nuclear factor (NF)-κB and activator protein (AP)-1 signalling pathways. The fold-change threshold is ± 2 (P < 0·05)

		UVA (dead) vs. control		UVB (dead) vs. control
		Fold change	P-value	Fold change	P-value
MAPK1 (ERK)			ns		ns
MAPK8 (JNK)			ns		ns
AP-1	JUN (c-Jun)	5·3	0·009	2·5	< 0·001
	JUND	2·6	0·011		ns
	FOS		ns		ns
	FOSB	7·86	0·019	3·27	0·021
NF-κB	NFKB1 (p50/p105)		ns		ns
	NFKB2 (p52/p100)		ns		ns
	RELA (p65)		ns		ns
	RELB		ns		ns
	REL (c-Rel)		ns	−2·5	0·042
IκB	NFKBIA		ns		ns
TP53 (p53)			ns		ns

ERK, extracellular signal-regulated kinase; IκB, inhibitor of κB; JNK, c-Jun N-terminal kinase; ns, not significant.