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. 2014 Dec 9;156(2):576–588. doi: 10.1210/en.2014-1026

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Figure 4. — LH and FSH responses to agonists of NK1R (GR73632) and NK2R (GR64349) in prepubertal rats. Effects of acute icv administration of the agonists of tachykinin receptors, NK1R (NK1R-A, GR73632) and NK2R (NK2R-A, GR64349) on LH and FSH release in prepubertal (25 day old) female (A and B) and male (C and D) rats. NK1R-A (600 pmol) or NK2R-A (600 pmol) were acutely icv injected and blood samples for hormone determination were taken at 20 and 60 minutes after injection of the compounds; animals injected with vehicle (VEH) served as controls. Groups with different superscript letters are statistically different (P ≤ .05), as estimated by a two-way ANOVA followed by a Tukey post hoc test.