Table 3.

Solubility of rotigotine in various solvents

Phase type	Solvent	Solubility (mg/mL)
Oil phase	Olive oil	10.25±0.16
	Labrafil® M 1944 CS	47.22±0.27
	Labrafac® Lipophile	46.32±0.34
	Oleic acid	16.16±0.13
Surfactant	Tween®80	13.1±0.16
	Labrasol®	87.47±0.32
	Cremophor®RH40	21.36±0.26
Cosurfactant	Transcutol® HP	259.85±0.68
	PEG-400	110.06±0.45
	1,2-propylene glycol	8.83±0.14
	Absolute ethyl alcohol	99.81±0.28

Note: Each data represents the mean ± SD (n=3).

Abbreviations: PEG, polyethylene glycol; SD, standard deviation.