Figure 2.

Binding capacity of ficolin-2 (a) and ficolin-3 (b) to acetylated bovine serum albumin (acBSA) at five predetermined time-points in patients undergoing cardiopulmonary bypass with Phisio®- (n = 15) or Bioline®-coated circuits (n = 15). At T0 the ficolin-3 binding capacity was significantly lower in the Bioline® group (P = 0·02). The difference was constant and no change in binding potential occurred over time in any of the groups. For ficolin-2 there was no difference at T0. However, the ficolin-2 binding capacity decreased significantly from T0 to T1 (P < 0·0001) in the Bioline® group and did not return to baseline level after 24 h, whereas the level was stable in Phiso® and the concentration stayed low. Bars show mean with 95% confidence intervals.