Figure 1.

Psoriasis patients have a high abundance of serum amyloid A (SAA) in lesional skin. (a) The expression level of SAA mRNA was quantified by real-time reverse transcription–polymerase chain reaction (RT–PCR) in normal (n = 8), psoriatic non-lesional (n = 11) and lesional (n = 11) epidermal samples, and the data were normalized against the amount of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) mRNA. Gene expression is graphed as mean fold induction over normal skin ± standard error of the mean (*P < 0·05). (b) Immunohistochemical detection of SAA proteins in representative normal and psoriatic lesional epidermis. Scale bars represent 10 μm in figures labelled ×40, and 20 μm in figures labelled ×20.