Figure 1.

Renal tissue from patients with immunoglobulin A nephropathy (IgAN) was stained for the presence of CD3, C4d, transglutaminase2 (TGase 2) and protein kinase intracellular signalling molecule (p-ERK)1/2. Representative images are shown. (a,e) CD3 staining of infiltrating T cells in renal interstitium, severe and mild, respectively. (b,f) A representative glomerulus showing positive and negative staining for C4d, respectively. (c,g) Kidney tissue showing strong and mild glomerular and tubulointerstitial staining for TGase 2. (d,h) A glomerulus showing strong and mild staining for p-ERK1/2.