Table 2.
Differential gene expression of Mycobacterium tuberculosis infected monoytes from elderly tuberculosis patients versus elderly Quantiferon-positive controls
| GenBank no.1 | Name | Log2 FC2 | GenBank no.1 | Name | Log2 FC2 |
|---|---|---|---|---|---|
| Signal transduction | Solute carriers | ||||
| NM_003331 | TYK2 | +2·76 | NM_003562 | SLC25A11 | +1·98 |
| NM_021913 | AXL | +2·15 | NM_017877 | SLC35F6 | +1·78 |
| NM_001136029 | DEPDC5 | +2·02 | Ubiquitination | ||
| NM_001087 | AAMP | +1·98 | NM_015710 | GLTSCR2 | +2·46 |
| NM_014216 | ITPK1 | +1·84 | NM_015528 | RNF167 | +1·97 |
| NM_006148 | LASP1 | +1·68 | NM_181575 | AUP1 | +1·91 |
| NM_024776 | SGK269 | −1·49 | NM_006677 | USP19 | +1·78 |
| NM_016038 | SBDS | −1·65 | NM_020429 | SMURF1 | −1·42 |
| NM_015656 | KIF26A | −3·18 | Other functions | ||
| Vesicle processing | NM_001402 | EEF1A | + 2·59 | ||
| NM_032389 | ARFGAP2 | +2·44 | Translation elongation factor | ||
| NM_014063 | DBNL | +2·42 | NM_006816 | LMAN2 | +2·41 |
| NM_033198 | PIGS | +2·30 | Lectin | ||
| NM_176812 | CHMP4B | +1·83 | NM_130395 | WRNIP1 | +1·84 |
| NM_201434 | RAB5C | +1·71 | DNA synthesis | ||
| NM_184231 | NCKIPSD | +1·66 | NM_022830 | TUT1 | +1·81 |
| NM_031899 | GORASP1 | +1·56 | Terminal uridylyl transferase | ||
| NM_013306 | SNX15 | +1·47 | NM_032116 | KATNAL1 | −2·23 |
| NM_014328 | RUSC1 | +1·35 | Microtubule dynamics | ||
| NM_044472 | CDC42 | −1·64 | NM_018402 | IL26 | −3·47 |
| NM_153235 | TXLNB | −3·87 | Cytokine | ||
| Transcription | NM_007185 | TNRC4 | −3·74 | ||
| NM_032204 | ASCC2 | +2·31 | RNA processing | ||
| NM_001950 | E2F4 | +2·15 | Unknown function | ||
| NM_032377 | ELOF1 | +1·88 | NM_015926 | TEX264 | +2·37 |
| NM_001002878 | THOC5 | +1·86 | NM_033296 | MRFAP1 | +2·32 |
| NM_001350 | DAXX | +1·63 | NM_016732 | RALY | +2·16 |
| NM_014815 | MED24 | +1·60 | NM_015680 | CNPPD1 | +2·08 |
| NM_001002259 | CAPRIN2 | −1·70 | NM_001033088 | NGRN | +2·04 |
| NM_006454 | MXD4 | −1·95 | NM_024589 | ROGDI | +2·03 |
| NM_015208 | ANKRD12 | −2·10 | NM_021943 | ZFAND3 | +1·84 |
| NM_04381 | ATF6B | −3·17 | NM_025078 | PQLC1 | +1·82 |
| Metabolism | NM_001006109 | DC12 | + 1·81 | ||
| NM_002629 | PGAM1 | +2·89 | NM_015609 | SZRD1 | +1·64 |
| NM_212461 | PRKAG1 | +2·25 | NM_144611 | CYB5D2 | +1·62 |
| NM_000116 | TAZ | +2·19 | NM_057161 | KLHDC3 | +1·46 |
| NM_002631 | PGD | +1·89 | NM_018259 | TTC17 | +1·36 |
| NM_138387 | G6PC3 | +1·75 | NM_001145450 | MORN2 | −1·88 |
| NM_025233 | COASY | +1·65 | NM_080764 | ZNF280B | −2·84 |
| NM_012239 | SIRTUIN3 | +1·64 | |||
| NM_021100 | NFS1 | +1·38 | |||
| NM_000353 | TAT | −4·76 | |||
Note: Genes are organized by gene function categories.
GenBank accession number.
Log2 fold change.