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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: J Magn Reson Imaging. 2014 Jun 19;41(5):1374–1382. doi: 10.1002/jmri.24663

Table 2.

Volume fraction (VF) changes of cluster 1, 2, and 3 in responders vs. non-responders. Using ROC curve analysis, the cutoff values of volume fraction (VF) changes of clusters 1, 2, and 3 were determined to predict chemotherapeutic response in bladder cancer.

VF change Responders
Mean (95% CI)		 Non-responders
Mean (95% CI)		 p-value Cutoff value (Sens., Spec., Acc.)
Cluster 1 −9% (−14%, −3%) 12% (−1%, 24%) 0.002 4% (87%, 71%, 83%)
Cluster 2 15% (8%, 20%) −15% (−28%, −2%) < 0.001 1% (96%, 100%, 97%)
Cluster 3 −5% (−11%, 0%) 3% (0%, 5%) 0.005 −1% (74%, 86%, 77%)