FIG 2.

Ratio of TB-specific to mitogen-induced responses. Whole blood was stimulated with M. tuberculosis-specific antigens (ESAT-6, CFP-10, and TB7.7) or with mitogen for 24 h, and the levels of TB-specific and mitogen-induced cytokines and chemokines were measured in active TB patients, LTBI subjects, and non-TB healthy control subjects. (A) Ratios of TB-specific to mitogen-induced responses are shown. (B) Comparison of TB-specific and mitogen-induced IP-10 levels. (C) The optimal cutoff value and positive cases are indicated on the graph. *P < 0.05; **P < 0.01; ***P < 0.001; ns, not significant.