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. 2015 Jan 15;4:23. doi: 10.1186/s40064-015-0787-z

Figure 2.

Figure 2

Representative examples of the sequencing analysis of potential ATM mutations in sporadic breast cancer patients. A, upper panel: reference sequence; B, middle panel: sequencing electropherograms from normal tissue samples from breast cancer patients (227 N, 231 N, 214 N, and 72NL); C, lower panel: sequencing electropherograms from tumor tissue samples from breast cancer patients (227 T, 231 T, 214 T, and 72TL). Case 227 showed two potential ATM missense mutations without evidence of LOH; Cases 214 and 231 showed potential ATM mutations with evidence of loss of the wild type allele.