Table 3.
Univariate analysis for disease free survival
| Unadjusted hazard ratio | 95 % Confidence interval | P value | |
|---|---|---|---|
| Nodes | 3.55 | 1.36–9.25 | 0.01 |
| Positive | |||
| Negative | |||
| Tumor thickness | 7.4 | 1.7–33.0 | 0.009 |
| <5 mm | |||
| >5 mm | |||
| Smoking | 0.78 | 0.28–2.14 | 0.64 |
| Sex | 0.76 | 0.29–1.97 | 0.57 |
| Age | 1.01 | 0.98–1.05 | 0.43 |
| Differentiation | 0.92 | 0.31–2.77 | 0.88 |
| Tumor budding | 1.32 | 0.59–2.95 | 0.49 |
| Pattern of invasion | 1.39 | 0.59–3.29 | 0.45 |
| Perineural invasion | 0.89 | 0.34–2.27 | 0.81 |
| T stage | 0.87 | ||
| 0.64 | 0.19–6.95 | 1.16 | |
| 0.99 | 0.11–3.94 | 0.65 | |
| Bone involvement | 2.44 | 0.41–14.64 | 0.33 |
| Skin involvement | – | – | – |
Univariate analysis showing that Positive nodes and Tumor thickness > 5mm are significant for reduced disease free survival