Skip to main content
. 2014 Apr 16;34(16):5486–5496. doi: 10.1523/JNEUROSCI.4861-12.2014

Figure 6.

Figure 6.

Leptin sensitivity of Kv2-family delayed rectifier channels. A, Top, Representative K+ currents from HEK cells expressing GFP-Kv2.1 with LepRb before and after the addition of 100 nm leptin. Calibration: 5 nA, 50 ms. Bottom, Mean G–V curves for the Kv2.1 current with and without leptin. B, Top, Representative K+ currents from HEK cells expressing GFP-Kv2.2 with LepRb before and after the addition of 100 nm leptin. Calibration: 5 nA, 50 ms. Bottom, Mean G--V curves for the Kv2.2 current with and without leptin. C, Mean G–V curve for Kv2.1 current after Src inhibition by the coaddition of 1 μm SrcI1 and 100 nm PP1 with and without leptin.