Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Improved insulin signaling in the liver of ob/ob mice treated with AMP-DNM. Animals were fed for 2 weeks with 0, 5, or 25 mg AMP-DNM/kg. To animals starved overnight, insulin (0.75 units/kg) was administered via the vena porta. Livers were collected after 5 min. Insulin receptor protein, and its autophosphorylation, and mTOR protein, and its serine phosphorylation, were visualized and quantified.
