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Dose-escalation of GTI-2040 in combination with high-dose AraC.
| Dose level | GTI-2040 CIVI days 1–6 (mg/kg/day) | AraC IV q24 h days 2–6 (g/m2/dose) | Cummulative dose AraC (g/m2) | Number of patients treated |
|---|---|---|---|---|
| 1 | 3.5 | 1.5 | 7.5 | 3 |
| 2 | 5 | 1.5 | 7.5 | 3 |
| 3 | 5 | 2 | 10 | 6 |
| 4 | 7 | 1.5 | 7.5 | 4 |
AraC, cytarabine; CIVI, continuous intravenous infusion.
