FIG. 2.
(A) Time course of functional recovery as measured using the extensor postural thrust (EPT) after crush injury and EGCG treatment. EPT was measured by calculating the functional deficit in this feature; thus, a higher value indicates a poor outcome. Note that CRUSH+EGCG rats displayed 50% improvement in motor recovery when compared to the CRUSH group. *p<0.01 and αp<0.05, CRUSH+EGCG rats compared to sham and naïve groups; Φp<0.001, CRUSH animals compared to CRUSH+EGCG, sham, and naïve groups. (B) The hopping test was done to test several integrated functions. The CRUSH+EGCG group displayed an early hopping response (as calculated by the percent of recovered animals) in the beginning of the third week postsurgery. *p<0.05, CRUSH+EGCG rats compared to CRUSH group; αp<0.05, CRUSH+EGCG rats compared to the naïve group; Φp<0.01, CRUSH animals compared to sham and naïve groups. EGCG, (-)-epigallocatechin-3-gallate; SEM, standard error of the mean.