Figure 1.

This is a schematic of the TumorGraft engraftment and testing process. A piece of the patient's tumor is collected at the time of surgery and implanted into immunocompromised mice for the purpose of propagation. While the patient recovers from surgery and receives treatment with first-line therapies, the TumorGraft is expanded across more mice (generations P0-P3). These engrafted mice eventually are enrolled in a drug-screening test to determine optimal treatments (RX). Test results are presented to the patient's treating oncologist to help guide later stages of therapy.